Immunology and Cell Biology

Immuno informatics & Systems immunology:

Immuno-informatics is forming models of disease states grounded upon these data sets. This core works with CIIID researchers to sort through the data to recognize specific gene functions within innate immune response networks that might be targets for therapy. It also classifies immune response gene networks from high-throughput data sets to identify biomarkers that permit us to assess how the immune system responds to infection, trauma, cancer and treatment.

Systems immunology can be defined as a broad strategy for understanding how a complex set of interacting components works to produce certain outcomes. Long ago, prescient immunologists coined the term ‘immune system’ in recognition of just how well this label fits the field, but for much of its long history, most insights into the immune system came from painstaking examination of the parts and their largely individual properties and not so much of activities across the whole system.