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Loredana Frasca


Loredana Frasca

Istituto Superiore di Sanita, Italy

Biography

Loredana Frasca obtained her Biological Science degree in 1992 and her PhD in Cellular Immunology in 1996. She has expertise in cellular immunology with the particular focus on T-cells, antigen presentation and T-cell tolerance. She has also expertise in innate immunity, in particular in regulation of dendritic cells functions. In the last ten years she worked on activation and homeostasis of T-cells and dendritic cells in normal responses and autoimmunity. Most recent research is focused towards the identification of pathogenic pathways that activate both innate and adaptive immunity in autoimmune diseases such as psoriasis, lupus, systemic sclerosis and arthritis.

Abstract

Abstract : Anti-carbamylated and anti-citrullinated LL37 antibodies are present in psoriatic arthritis (PsA) patients and are potential markers of disease together with GM-CSF and IFN-α