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Marlene Bouvier

University of Illinois at Chicago, Franc

Biography

Marlene Bouvier’s laboratory has been interested, for the last 20 years, in characterizing molecular and structural mechanisms involving MHC class I molecules with respect to peptide loading, selection, and processing, as well as how these events are modulated by interaction with specialized proteins of the endoplasmic reticulum

Abstract

Abstract : ERAP1-ERAP2 dimers trim MHC I-bound precursor peptides; understanding peptide editing