Dr. Charles J. Malemud
Editor-in-Chief, JCCI
Case Western Reserve University
USA
Biography
Charles J Malemud received the PhD from George Washington University in 1973 and completed postdoctoral studies at the State University of New York at Stony Brook in 1977. He is Professor of Medicine & Anatomy in the Division of Rheumatic Diseases and Senior Investigator in the Arthritis Research Laboratory at Case Western Reserve University School of Medicine. He has published more than 200 papers and reviews primarily in the field of chondrocyte biology. He is on the editorial board of several rheumatology, immunology and musculoskeletal journals and is Editor-in-Chief of the Journal of Clinical and Cellular Immunology.
Research Interest
Biology of the Musculoskeletal System Intracellular Signal Transduction Pathways Inflammation Pro-inflammatory, Anti-Inflammatory & Anabolic Cytokines Apoptosis Matrix metalloproteinases Osteoarthritis Rheumatoid Arthritis Fibromyalgia Autoimmune Disorders Research Interest
Dr. Sudhir Gupta
Professor of Medicine, Chief, Division of Basic and Clinical Immunology Director, Programs in Primary Immunodeficiency and Aging
University of California
USA
Biography
Sudhir Gupta is a Professor of Medicine, Pathology & Laboratory Medicine, and Microbiology & Molecular Genetics, Chief of the Division of Basic and Clinical Immunology, and the Director of the Jeffrey Modell Diagnostic Center in Primary Immunodeficiencies at the University of California, Irvine. He also serves as Director of Scientific Development at the Sass Foundation for Medical Research in New York. Dr Gupta received his medical and doctorate degrees from the King George's Medical College in Lucknow, India. Previous appointments include Associate Professor of Medicine and Immunology at the Weill Cornell Medical College, and Associate Member at the Sloan-Kettering Institute for Cancer Research, both in New York, New York. Dr Gupta is board certified in Clinical Immunology by the Royal College of Physicians and Surgeons of Canada; he is board certified in Allergy and Immunology, and Diagnostic Laboratory Immunology by the American Board of Allergy and Immunology. Dr Gupta is a Master of the American College of Physicians. Dr. Gupta has served on a number of committees for many leading governmental bodies and organizations, including the National Institutes of Health, the U.S. Food and Drug Administration, and the World Health Organization. Dr Gupta has made many original contributions in the field of cellular and molecular immunology as it relates to primary immunodeficiency diseases, AIDS, cancer research, and aging. These findings have been published in high-impact journals, including Science, Nature, the Proceedings of the National Academy of Sciences, the Journal of Experimental Medicine, the Journal of Clinical Investigation, the New England Journal of Medicine, and Aging Cell. Dr Gupta has published more than 500 scientific papers, invited reviews, and book chapters. He has edited 24 books in various areas of cellular, molecular, and applied immunology, including one on primary immunodeficiency.
Research Interest
Molecular signaling of apoptosis, Dendritic cell biology, B cell biology, Genetic basis of primary immunodeficiency diseases
Dr. Michael Andrew Tainsky
Professor, Department of Oncology
Wayne State University
USA
Biography
Michael Tainsky is a molecular cell biologist who has been studying the molecular basis of human cancer for more than 30 years. In 1998, he came to the Karmanos Cancer Institute at Wayne State University School of Medicine after 13 years on the faculty of the University of Texas, M.D. Anderson Cancer Center in Houston, TX, and 8 years at NCI/NIH. He has studied the biological effects of oncogenes, tumor suppressor genes, and transcription factor on tumor cells; and in the Li-Fraumeni Cancer Syndrome, he studied the mechanisms of cellular immortalization. Recently, he extended his mechanistic cancer research to translational applications of genomics and proteomics to molecular diagnostics of ovarian cancer. For the past 10 years, his laboratory team has developed the epitope cloning technology and protein microarray immunoassays to detect tumor autoantibodies in patients’ sera. His Epitomics Biomarker Technology identifies the autoantigen biomarkers using novel informatics tools for the classification of patients. In 2009, he published a 330-page book as editor in the Methods in Molecular Biology Series from Humana Press entitled Tumor Biomarker Discovery. He was invited to guest edit Special Issues of the journal Cancer Biomarkers on Antibody Biomarkers and Biomarkers in Ovarian Cancer. Dr. Tainsky holds the Barbara and Fred Erb Chair in Cancer Genetics at the Barbara Ann Karmanos Cancer Institute. He is a professor in the Department of Oncology.
Research Interest
Molecular genetic mechanisms by which normal cells become malignant • Pathway analysis of gene expression changes leading to cellular immortalization • Development of novel cancer diagnostic tests for early detection of cancer in the form of a complex blood test
