Noelle Mathieu
Institute of Radioprotection and Nuclear Safety (IRSN), France
Biography
Noëlle Mathieu has a thesis in Immunology from the Marseille-Luminy Immunology Center, France. She joined the Institute of Radioprotection and Nuclear Safety near Paris. Her project consists in studying late side effects of pelvic radiotherapy and developing therapeutic strategies. She used pre-clinical animal models of localized irradiation to the colorectum and developed endoscopy technique and surgery in rats. She used this model to understand the physiopathology of radiation proctitis and used cell therapy using mesenchymal stromal cells to reduce radio-induced damaged to the colon. Her studies contribute to the use of this treatment in compassional case of patients who had a surdose of ionizing radiation during their radiotherapy protocol. She is also involved in combined therapy to improve the actual treatment.