Immunology

Biography

Peyman Obeidy`s fundamental research interest is the integration of cancer biology, immunology and biophysics. During his postdoctoral work at Professor Wolfgang Weninger’s laboratory, he manipulated the expression of Arp2/3, one of the critical actin nucleators, by the shRNA-mediated knockdown. Findings from this study expand our knowledge of the regulation of the actomyosin cortex in T cells. His PhD study was focused on dissecting the molecular mechanisms that underpin the functional specialization of the actin cytoskeleton. Using fluorescence imaging and single-molecule analysis, he developed microfluidics assays and succeed in detecting the binding of single tropomyosins into polymers with actin in vitro. In the biomedical field, he worked on the development of applications and assays which pave the way for more accurate and accessible therapies.

Abstract

Abstract : Critical functional and morphological role of Arp2/3 in T lymphocytes