Immunology

Biography

Postdoctoral Research at Mayo Clinic, Rochester, USA (2014-2015), University of Illinois at Chicago, USA (2010-2014), Indian Institute of Toxicology Research, Lucknow, India (2009-2010). His research interests focus on the role of macrophages in the initiation, progression and resolution of inflammatory processes. The long term research interest is to elucidate the inflammatory signaling in macrophages during chronic and acute inflammation. Macrophage recruitment and plasticity are key components of several inflammatory diseases including asthma, fibrosis/cirrhosis, rheumatoid arthritis and atherosclerosis. Understanding the mechanisms that regulate macrophage phenotypic plasticity in tissues is critical for the identification and validation of markers and therapeutic targets in inflammatory diseases.
Awards 2010: Ramanujan Fellowship Award
2014: Ramalinga Swami Fellowship Award
2013: Mirus Research Award, Mirus Bio LLC, USA
2009: Research Bursary Award, UK
2008: FEBS Pre Doctoral Award , Greece
e Cheminfo Award, USA
2007: EMBL International Ph.D Fellow Award
2007: Research Travel Grant Award, USA

Abstract

Abstract : NOS1-derived nitric oxide promotes NF-kB stability and transcriptional activity by inhibiting suppressor of cytokine signaling (SOCS-1) in response to TLR4 activation