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Johnny Huard

Johnny Huard

Visiting Distinguished Wallace Professor and Vice Chair – Research Department of Orthopaedic Surgery at The University of Texas Health Science Center at Houston Medical School


Prior to joining the University of Texas Health Science Center at Houston and the Steadman Philippon Research Institute, Dr. Huard held the Henry J. Mankin endowed Chair in the Department of Orthopaedic Surgery and was the Director of the Stem Cell Research Center (SCRC) at the University of Pittsburgh for twenty years. Dr. Huard was also the deputy director for Cellular Therapies at the McGowan Institute for Regenerative medicine at the University of Pittsburgh. rnrnHe has extensive knowledge in the areas of gene therapy, tissue engineering & regenerative medicine applications based on the use of muscle-derived stem cells. His primary areas of interest are in basic stem cell biology and their translation to clinic to aid in the healing and regeneration of a variety of musculoskeletal tissues. His research team has received national and international recognition, and the technologies that we have developed, have been licensed to industry. The muscle derived stem cells that have been isolated by my team are currently undergoing clinical trials for the treatment of urinary stress incontinence (SUI) and myocardial infarction. Dr. Huard’s current major research interests include: Skeletal muscle stem cell isolation and their characterization (origin, gender and age effect); Alleviation of the muscle degeneration associated with Duchenne’s muscular dystrophy through muscle derived stem cell transplantation; Bone and articular cartilage regeneration through stem cell transplantation; Cardiac and skeletal muscle injury repair, regeneration, and fibrosis prevention; Peripheral nerve regeneration using MDSCs; The use of MDSCs as a source for paracrine factors to alleviate the phenotypic changes associated with natural aging and progeria. He and his team have published over 300 peer reviewed papers, 82 book chapters, and have had 757 abstracts accepted for presentation at national and international conferences.rnrn


Abstract : The role played by the host inflammatory cells in adult stem cells mediated tissue repair

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