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Ahmed Gaffer Hegazi

Ahmed Gaffer Hegazi

National Research Centre, Egypt

Title: Cytokines pattern of rats infected with Toxoplasma Gundii and supplemented with Capparis Spinosa honey

Biography

Biography: Ahmed Gaffer Hegazi

Abstract

Objectives: This study was conducted to investigate the cytokines pattern of rats infected with Toxoplasma Gundii and supplemented with Capparis Spinosa honey (Saudi Arabia) for a period of 28 days.

 

Methods: Immunoglobulin M, immunoglobulin G, and cytokines were detected by using enzyme-linked immunosorbent assays (ELISAs). In addition, the mortality and the morbidity rates were assessed.

 

Results: Oral administration of Capparis spinosa honey as a natural food additive was experimentally shown to increase the antibody titer; furthermore, compared with the rats in the control group, the levels of the sera cytokines (IFN-γ, IL-1 and IL-6) were consistently higher at day 7 post-infection in the infected rats treated with oral supplements of Capparis spinosa honey.

 

Conclusion: Orally administered supplements of Capparis spinosa honey increased both the antibody titer and the cytokines (IFN-γ, IL-1 and IL-6) levels in rats infected with Toxoplasma gundii.