Fayez M Al Guthami, Ahmed F.M. Al Gethami, Ahmed Hegazi
Makkah Bee Association, KSA
Title: Influence of administration of Capparis spinosa honey on immune response of infected rats with Toxoplasma gundi
Biography
Biography: Fayez M Al Guthami, Ahmed F.M. Al Gethami, Ahmed Hegazi
Abstract
This study conducted to investigate the immunological responses of rats infected with Toxoplasma gundi and treated with 15% Capparis spinosa honey (Saudi Arabia) supplemented orally for a period of 35 days. Immune response of rats was evaluated weekly. Cytokines were detected in honey supplement either in non-infected or infected. Mortality and morbidity rate were assayed where the lymphoid organs weight were determined. The results revealed that oral administration of honey as a natural feed additive through the experiment reduced mortality rates, increase in body weight, lymphoid organ weight. Also antibody titer was raised. Serum levels of cytokines were consistently higher in the infected and honey supplemented rats compared with controls. Serum levels of IFN-γ, IL-1 and IL-6 were elevated only at day 14 post- infection.