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Fayez M. Al Guthami, Ahmed F.M. Al Gethami, Ashraf M Barakat,

Makkah Bee Association, KSA

Title: Egyptian propolis 12: Influence of propolis on cytokines of Toxoplasma gundi infected rats

Biography

Biography: Fayez M. Al Guthami, Ahmed F.M. Al Gethami, Ashraf M Barakat,

Abstract

This study was conducted to investigate the influence of propolis on immunological responses with special reference to cytokine level of infected with Toxoplasma gundi and treated with and then the inoculation with 0.1 ml propolis everyday till the end of the experiment (28 days). Immune response of rats was evaluated weekly. Cytokines were detected. The results revealed that the growth promoting effect propolis extract. It was clear that the propolis treated group showed the highest lymphoid organ weight all over the experimental period. Propolis was the highest in the Toxoplasma antibodies titer when comparing with control group from the 2nd week to the end of experiment. Serum levels of cytokines were consistently higher in the treated and propolis infected rats compared with controls. Serum levels of IFN-γ, IL-1 and IL-6, were elevated only at day 7 post-infection.