Kimihiko Okazaki
Japan Medical Association, Japan
Title: An irrelevant concept that has long been taken for granted as relevant
Biography
Biography: Kimihiko Okazaki
Abstract
It has long been taken for granted that all of antibody molecules rigidly combine with their receptors. On the other hand, it is well established that an equilibrium state exists among antibody molecules in the vicinity of their receptors. These two concepts obviously disagree with each other. Namely, either one of these two concepts ought to be wrong. However, the concept of existence of equilibrium can't be wrong since it has been established more recently than the other one, which used to be believed presumptively. Apparently, contemporary immunologists should be aware of the contradiction. Unfortunately, they don't seem to be so. It seems to me that authoritative immunologists, at least, are aware of it because they must not be stupid enough not to be aware of the contradiction. I'm afraid that they are just too egocentric to admit the irrelevancy. For them, it is more important to keep their research problems unfinished than to heal autoimmune diseases. In my opinion, purpose of medical research is to save sick people applying the best treatment for their diseases. Applying the relevant concept, the pathogenic antibodies can easily be replaced from the responsible cells, i.e., cytolytic T lymphocytes, by accumulating non- pathogenic antibodies in the body of the patient. The latter can be accomplished by repeating intradermal injections with non-specific antigens. I do have numerous cases of successful healing of autoimmune and allergic diseases. I have no case of failure. In conclusion, it is about time for authoritative contemporary immunologists to admit my idea.