Thomas Grundström
Umeå University, Sweden
Biography
Thomas Grundström completed his doctorate at Umeå University in 1981 and his Medical degree in 1982. Dr. Grundström was post-doc 1982-1984 in the laboratory of prof. Pierre Chambon, Strasbourg, France, where he characterised the first discovered enhancer of transcription. He is professor at the department of Molecular Biology at Umeå University since 1994. Dr. Grundström discovered the first direct Ca2+/calmodulin inhibition of a transcription factor (Corneliusen et al., Nature, 1994) and has characterized the Ca2+ regulation of many regulatory proteins with a focus on the immune system. Dr. Grundström is presently studying regulation of production of high affinity antibodies.
Abstract
Abstract : Regulation of diversification and affinity maturation of antibodies