Roswitha Gropp
Hospital of Ludwig-Maximilians-University, Germany
Biography
Roswitha Gropp has over 25 years of experience in preclinical development and infl ammatory diseases. She recently took on a different view considering the infl ammatory process in UC as an uncontrolled wound healing process. This hypothesis assumes that epithelial damage induces the release of signals to evoke a Th2 characterized infl ammatory response that ultimately results in repair of the colon. Using agent based modeling fi rst disease maps were developed to describe the infl ammatory milieu and the dynamics of the infl ammatory response. This approach together with immunological profi ling of patients allows for a better understanding of underlying mechanisms ultimately leading to individualized therapies.