Hematopoiesis and Immune System Development

Haematopoiesis is the synthesis and development of Blood cells. Occurs during embryonic development and throughout adulthood to produce and replenish the blood system. Cellular blood components are derived from haematopoietic stem cells that reside mainly in the bone marrow, a major site of adult haematopoiesis. The blood system contains more than 10 different blood cell types with various functions: Leukocytes represent many specialized cell types involved in innate and acquired immunity. Erythrocytes provide O2 and CO2 transport, whereas megakaryocytes generate platelets for blood clotting and wound healing.

Immune System Development:

Our immune system defends people against germs and microorganisms. The immune system consists of lymphoid organs that can be divided into the primary and secondary immune systems as well as the myeloid and lymphoid cells, these arise via haematopoiesis. The primary lymphoid organs are the bone marrow and thymus. These are the sites at which haematopoiesis occurs and immature lymphocytes grow, develop, and differentiate. The secondary, or peripheral, lymphoid organs primarily consist of the spleen and lymph nodes and play roles in antigen presentation and adaptive immune response initiation.

 

  • Hematopoietic stem cells
  • Myeloid and erythroid cells
  • Lymphoid organs development

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